in spite of oneself, try as one might, no matter how hard one may try (to, not to)
When paired with a negative verb or adjective,
Used often with potential verbs in the negative to mean 'no matter how hard I try, I cannot do it', or with regular negative verbs to mean 'for some reason, it doesn't happen'.
朝は
No matter how hard I try, I cannot wake up in the morning.
Used with negative い-Adjectives or な-Adjectives to indicate that the speaker has a vague feeling that something isn't quite right or simply feels it isn't a certain way, translating to 'I don't know why, but it isn't...'
この本は
I don't know why, but this book just isn't interesting.
その色は
For some reason, I just don't like that color.
When used with verbs, it is most natural to use the potential form of the verb to emphasize the inability to perform the action despite one's best efforts.
When paired with conjecture expressions like らしい or ようだ,
Adds a sense of vague conjecture to a verb, indicating the speaker gathers that an action will happen or has happened.
明日は
From what I gather, it seems like it will snow tomorrow.
Combines with an い-Adjective to express that something appears to have a certain quality, based on the speaker's intuition or gathered clues.
外は
It seems that it is cold outside.
Combines with the stem of a な-Adjective to express a hunch about a certain state or characteristic.
あの店は
From what I gather, that store seems to be famous.
Although